Interesting bit during Quake Con: They have a feature planned where players can run "expeditions" to areas outside West Virginia (like a dungeon run basically). Their plan is to show off areas that haven't been shown off in Fallout before and some fanservice areas. They also have a plan for instanced vault-like bases for players that have less restrictions on placement and budget limits.
Considering WV's location, I suspect the fanservice areas would probably be DC, the Pit, Boston, or maybe Mothership Zeta (in portion anyways).