First of all, who cares if you die in the lab. A key costs a few chaos and the opportunity cost of 15 minutes... but it's a learning process so consider it an investment. For comparison, I spent 400 chaos learning Uber Atziri this league.
Once you scale your character up to some appropriate end-game level, you're incredibly unlikely to die to Izaro -- assuming sensible build design. He isn't a high-level boss, and while doing triple key runs introduce
some risk, you ought to kill him so fast he barely gets a chance to do anything. If your Izaro fights last longer than 5-10 seconds because of DPS (i.e., not because you're letting him charge up for double and triple key) then you don't have enough DPS and need more gear.
You'll also start to see the pattern that all Lab zones operate under. Example: an objective will almost assuredly be "down and to the left" of zone in, and another will be "up and to the right" from that... etc etc. My slow-as-fuck SRS build was clearing labs with some side objectives in ~15 minutes. Actual good lab builds aim for much much quicker runs.
Uber lab notes
^ Great resource. Sometimes its just better to go run maps, sometimes the Lab is a super fast 6 room run.