Science!! Fucking magnets, how do they work?
- Thread starter Flunklesnarkin_sl
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Guest, it's time once again for the massively important and exciting FoH Asshat Tournament!
Go here and give us your nominations!Who's been the biggest Asshat in the last year? Give us your worst ones!
Ukerric
Bearded Ape
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It is when the information you want to protect using secret keys is extremely sensitive, and you do not want a third party to get it.
The problem with communicating a secret key is that, if it's intercepted and copied, the information exchanged with that cryptokey is compromised. Quantum entanglement gives you a guarantee that nobody "listened" to your key exchange, because if they did, the key received at the end will not be correct.
Of course, to secure your porn viewing habits, it's not worth it. But to secure bank-to-bank finantial transactions (or even better, military talks), that's covering the risk.
Note that if you try to man-in-the-middle that (fake being the receiver, and recreating a key as a fake sender), it is also detectable because your "entangled photons" arrive at slower than the speed of light (because you have to decode and recode), and a round-trip measurement show that someone is doing hanky-panky in the middle.
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Tuco
I got Tuco'd!
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I don't know genetics but I'm extremely excited about genetic engineering. I feel like it'll make so many health and cultural issues that are the forefront of today's challenges look antiquated like scurvy.
ZyyzYzzy
RIP USA
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Technical limitations, lack of testing, and a few too many unknowns at this point. It'll happen soon enough though.
I don't know genetics but I'm extremely excited about genetic engineering. I feel like it'll make so many health and cultural issues that are the forefront of today's challenges look antiquated like scurvy.
ZyyzYzzy
RIP USA
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Fuck you. I'm only 30. I can still hope we can progress genetic engineering so I have a chance of living indefinitely
Palum
what Suineg set it to
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ZyyzYzzy
RIP USA
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First and simplest clinical applications of genetic therapies will definitely be in adults (and children) and not be engineering zygotes that will be implanted into a womb and allowed to fully develoo.
Tuco
I got Tuco'd!
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Why? Or more specifically, how can genetic engineering help a fully formed human with a bajillion cells already genetically encoded?
ZyyzYzzy
RIP USA
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Completely pulled out of ass hypothetical.
Let's say you have a liver condition due to a genetic abnormality, some protein that is required for detoxification has much less affinity for its target ligands than the wild type. First, you can easily study said protein in vitro and work out targeted delivery of say a CRISPR/cas system with gRNA that targets hepatic progenitor cells. You can test it in vitro. You can test all of this in an animal model and get data on any desired and undesired effects of said delivery system and targetted genetic engineering of said protein. In theory, if the FDA isn't being a dick for the 5-10 years all of this takes, you can get this approved for clinical use.
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Ukerric
Bearded Ape
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See an old post of mine where I was exactly describing this. Embryo selection a-ok, but you're not allowed to select based on a number of characteristics.
I don't know genetics but I'm extremely excited about genetic engineering. I feel like it'll make so many health and cultural issues that are the forefront of today's challenges look antiquated like scurvy.
The reason why it's forbidden isn't because we don't know how to do it. The reason it's forbidden is that it's "Eugenics", and Eugenics triggers associations with old horrors.
Cad
scientia potentia est
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Thats stupid though, nobody has ever done eugenics that way and choosing which embryo to bring into the world doesn't burden any living people. The "old horrors" you're referring to involved sterilizing and/or killing people rather than selective breeding, but now they get lumped together as if you're a nazi if you imply certain genetic traits are better than others (e.g. bigger/stronger/faster/more healthy). It's fucking stupid.
iannis
Musty Nester
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Stem cells.
This kind of research is not only likely to be first. It has been the first.
There are a lot of miraculous applications for it. From anything as vain as curing scars to something as serious as curing cystic fibrosis or sicklecell.
Now how do you replace the entire basal layer at once without: 1) killing someone or B) triggering an autoimmune response?
That sounds like a pretty good question to answer.
This kind of research is not only likely to be first. It has been the first.
There are a lot of miraculous applications for it. From anything as vain as curing scars to something as serious as curing cystic fibrosis or sicklecell.
Now how do you replace the entire basal layer at once without: 1) killing someone or B) triggering an autoimmune response?
That sounds like a pretty good question to answer.
Tuco
I got Tuco'd!
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Yeah but isn't there a massive set of problems with replacing the liver cells with your new genetic liver? Or is your genetic engineered shit just some uhh, super soldier serum that does its job without changing the genetics of the person's organs?
ZyyzYzzy
RIP USA
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Huh? In my example you target liver progenitor cells to make a change in the gene of the protein that is a variant to a WT version (higher affinity for whatever its target is). In theory, hepatic progenitor cells should be highly targetable for the CRISPR/cas system specifically designed to target and change sequence of the protein of interest and since they aere progenitor cells, as they multiple, further differentiate, the genetic change should be present throughout the liver eventually
ZyyzYzzy
RIP USA
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Go build a robot that makes you cheeseburgers shitlordhepatic progenitor cells eh.
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