Initial impression, about 2 hours of using the X52 Pro.
First, it's a nice piece of hardware...lots bigger than I expected.
Second, it's confusing as hell to learn what all the buttons do. I'm using the default configuration since it seems to be a bit complicated to remap stuff.
Third, it's extremely fun to fly with it. I enjoy it a lot more, it's more intuitive.
Fourth, as far as I can tell you totally lose the use of gimbal weapons, they act as fixed weapons. That's a pretty big loss...and affects targeting a lot. Other than that though, I don't feel that it is harder to aim than with a mouse and keyboard. So if I equipped my ship with nothing but fixed weapon, I feel the X52 would be superior to mouse+keyboard. On a ship with a lot of gimbal weapons it would be inferior. I am honestly not familiar with the balance between all the weapons to say if gimbal vs fixed is balanced or not, but that seems to be the biggest issue.
Last, not exactly game related...but you need a lot of room on your desk for this setup, and I am guessing you'll need more when the FPS module is out, or the full game and you need to switch between mouse+keyboard for FPS and X52 for flight...although it probably won't be that frequent in a play-session...and load time are long enough that you can move everything, but still it takes a lot of room. Also, the USB cable is on the throttle which is to my left side...and my computer is to my right side...cable is kinda short which is really annoying.
All in all, it definitely seems to be the way I'll be going if they balance everything nicely, but as I said I'm gonna wait till closer to release to make a final decision. Also have the one my friend loaned me for a while, so I can practice some more.