Basic Controls and Settings - Starts at 0:01:05
Movement, use of powers
Help menu
Gameplay/keybinding settings
Powers and Characters - Starts at 0:04:33
Discuss power types (basic vs. spirit spenders, etc.)
Typical build type (Solid basic, movement, AOE, single target spirit spender for bosses, passives)
Character types (melee, ranged, hybrid)
Giving characters a 'fair chance'
Gear and Vendors - Starts at 0:10:54
Types of gear
Ubiquitous vendors
Leveling up vendors
Odin's Palace specific vendors
Stats, User Interface, and Windows - Starts 0:22:44
Map
Info windows (social, character change, inventory, log, synergies, etc.)
Story Versus Leveling Quickly - Starts at 0:29:53
Strategy - in general, go through story or level much faster
Quest Rewards
Strategy for leveling quickly (items, synergy, etc.)
Acquiring New Characters/Using the Inside and Outside of Game Stores - Starts at 0:46:11
Splinters
3 Methods for getting characters (splinters, G, Online Store)
Additional items for purchase
Interaction With Other Players - Starts at 0:53:00
Social window
Chat - New Functions in Patch 2.3
Supergroups
Parties
Trade
Etiquette (preferred, at least)
Endgame and Phat Lootz!!! - Starts at 0:59:03
Gear
PvP
Terminals - Re-organized in patch 2.3
X-Def
Holo Sim (added patch 2.3)
More characters
Prestige
New in 2.2 - Starts at 1:14:11
Runes, runewords, enchanting
Coming Soon - Starts at 1:18:37
New characters
Danger room
RRRAAAAAIIIIIDDDDDSSSSSS!!!!!!
Additional Tips and Hints - Start at 1:22:02
Additional legendary quest tips
DOOOOOOP!
Forums (aka this site)/MarvelBase
Inventory swapping
Closing Remarks/Thoughts - Starts at 1:33:43
So that's it. As I said, this is really intended for new(er) players who are having difficulties and I made it as comprehensive as I could, but there are obviously plenty of pieces I missed, so feel free to add in the comments. I hope that it can clear up at least some confusion with playing the game and introduce most of the important elements. Thank you and, once again, hope it helps!!