Reworked my Black Panther build and gear yesterday, he was already good but now he's ridiculous. He's one of the few characters you can build defensively and offensively at the same time because of his kit.
Right now I've got 22k hp, 13k all defenses, 48% dodge (might replace my blessings for fandral's to up that to 60%) 743 LOH, 22k hp regen per min, 50% crit and 6.5k dmg rating on his primary skills (predator's frenzy and savage strike).
His signature brut's for over 1 mil (highest so far is 1.4 mil), the dot portion of savage strike crits for 70k (ticks twice per second) and predator's frenzy crits for 80k. Add jungle snare on top of that and he just melts bosses and can clear packs efficiently too with knockdown sweep + jungle snare. It's beast mode. Only thing left I really need is a white suit jacket and I might replace his runeword for Lunar Eclipse for groups because I have small spirit problems when I'm not being attacked.