And even then, the foundation that helped fund that polio research and the Salk vaccine didnt disband. It actually still exists to this day, with its goal "fighting birth defects". Yeah, good luck with eradicating those.
I also think that these foundations were significantly different 60 years ago than today. Back then, they saw their mission as finite. After over half a century, there is such a culture developed around these foundations that they can run in perpetuity on the vaguest most open ended mission statement and generally do fuck all except get people like ham to harass everyone he knows for donations on their behalf.