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There needs to be incentives for exposing fraud or even just mistakes. You get rich and famous for positive results, not for finding things that don't work, so there's always an incentive to cheat and the incentive for exposing the cheats is to be the asshole that no on likes because they ruined so and so's career and got the funding pulled from the university. Not hard to guess why people aren't lining up to do it.
I suspect that part of the problem is that the "easy" stuff has all been figured out. What's left is very complex and science isn't that good at dealing with extremely complex things. An ideal experiment only has one variable and you can directly compare the experiment to the control and see the results. In medicine, nutrition, and a lot of other fields it's never like that. If you're doing an experiment on actual humans there's a thousand variables for every person that you can't really control for. It's no wonder why we still can't even figure out what we should eat.
I suspect that part of the problem is that the "easy" stuff has all been figured out. What's left is very complex and science isn't that good at dealing with extremely complex things. An ideal experiment only has one variable and you can directly compare the experiment to the control and see the results. In medicine, nutrition, and a lot of other fields it's never like that. If you're doing an experiment on actual humans there's a thousand variables for every person that you can't really control for. It's no wonder why we still can't even figure out what we should eat.