- 3,312
- 2,168
Haven't watched it yet, but I would assume it will be a debate.
I haven’t heard nearly as much of Brett as Eric. Seems like his drunk ahis share of looks is sometimes.Brett is the good Weinstein. Or the best of the two at least.
Anyone paying attention to this work?
How often people poop, they found, can have a large influence on one’s physiology and health.
Bowel movement frequency (BMF) directly impacts the gut microbiota and is linked to diseases like chronic kidney disease or dementia. In particular, prior work has shown that constipation is associated with an ecosystem-wide switch from fiber fermentation and short-chain fatty acid production to more detrimental protein fermentation and toxin production. Here, we analyze multi-omic data from generally healthy adults to see how BMF affects their molecular phenotypes, in a pre-disease context. Results show differential abundances of gut microbial genera, blood metabolites, and variation in lifestyle factors across BMF categories. These differences relate to inflammation, heart health, liver function, and kidney function. Causal mediation analysis indicates that the association between lower BMF and reduced kidney function is partially mediated by the microbially derived toxin 3-indoxyl sulfate (3-IS). This result, in a generally healthy context, suggests that the accumulation of microbiota-derived toxins associated with abnormal BMF precede organ damage and may be drivers of chronic, aging-related diseases.
Low/Zero carb diet people be like "2-3x a week? I wish."Timing is Everything: ISB Study Finds Link Between Bowel Movement Frequency and Overall Health
Everybody poops, but not every day. New research by ISB researchers suggests bowel movement frequency is linked to long-term health.isbscience.org
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If you don't poop at a normal frequency, microbes in your gut run out of soluble fiber and switch to fermenting amino acids, which leads to toxin production.
The biggest surprise to me in this study: there are people out there who only poop 2-3 times a week but consider themselves healthy. Its the "healthy at any size" equivelent in the world of digestive physiology. Holy shit man, if you're only pooping 2-3 times a week take the day off work TODAY and see a doctor TODAY.