If anyone has played both PF2 and DnD5e, I'd love to hear an analysis/comparison.
I think PF2e is overall a richer and deeper experience. Your character's combat and out-of-combat abilities develop independently, so you don't have to to sacrifice one to be good at the other, but there's still enough variety amongst non-combat activities that will require players to cooperate and specialize in different things. You also don't have to choose between feats or ability boosts - you'll get both through the course of leveling up. Classes are much less set in stone in PF2e than they are in 5e - your feat selections can make your Rogue play completely different from another Rogue.
The balance of the game is very tight. In 1e you could endlessly stack modifiers to make yourself a god, but in 2e, modifiers have been condensed into three different categories that don't stack with themselves. Additionally, there are static modifiers tied to your level, which results in an extremely tight math system that keeps the game's difficulty consistent throughout the adventure. (I.e., an enemy that is your level +3 will always be significantly powerful no matter what your level is, whereas an enemy equal to your level -3 will always be trivial.)
From a roleplaying perspective, PF2e's system allows you to create much more creative characters without needing to homebrew. The core rulebook itself has thousands of character options, and they've all been meticulously balanced to the point where there aren't really any "trap" selections (unless you specifically pick something niche and non-applicable to your situation, like a desert resistance feat in a snow-themed campaign).
Pathfinder 2e is also a multiclasser's dream. In D&D, you have to "take" a level in another class when you level up, which stops you from gaining a level in your base class. This is not the case in PF2e. Instead, you just trade an optional feat in your class for an optional feat in another class (with some limitations).
Speaking of classes, D&D 5e was released in 2014 and has 12 base classes. Pathfinder 2e released last year and already has 16, with two more on the way. 5e has many different archetypes for each base class, but PF2e's more flexible system of archetyping has over 50 different ones to choose from (and any can be accessed by any base class through the multiclassing system, provided they can meet the prerequsiite). Two more base classes are being released next summer, with several new archetypes in addition.
But better than all of that is PF2e's simplified action system. In 5e, each turn you have a move, an action, and a bonus action, and you have to keep track of what's what. In PF2e, it's simplified to three "actions." Want to move twice and attack once? You can do that. Want to attack three times in one turn at first level? You can do that too (though there is a stacking multiple attack penalty for taking multiple attacks in a turn). Some spells different casting "modes" that cause them to do different things when you invest more actions into them. (The Heal spell is touch with one action, 30ft range with two actions, or 30ft burst with three actions, for example).
I've had fun with 5e, but it gets old. I like to take my time to develop and really get into a character I'm going to be playing in a campaign that runs months. PF2e lets me do that, so I quit 5e when PF2e launched and haven't looked back.