The Wire is overrated. It's a good show, but it's still just a standard crime drama. I watched the whole series for the first time last year and I don't see what all the insane hype was about. Fifth season storyline with the fake serial killer was stupid as hell.
Lost was great at the time because it was a fantastic water cooler show to discuss and wonder about. In hindsight, it was just a big fucking tease with no clear storyline or ending.
Spartacus was super fun to watch, but it could be pretty cringey at times with awful acting and 1AM skinemax levels of softcore porn.
Game of Thrones is great on the first watch because it's got unexpected deaths and a fantastic, intricate storyline. It has almost zero rewatch value because all the story and surprise is gone.
The answer is Seinfeld. Funny at the time, infinitely rewatchable, and a huge cultural impact. If you didn't find it funny it means you're a bad person, so it's great as a test of character, too.