A study of the effects of non-nutritive sweeteners on human metabolism as well as their microbiomes reveals how these can induce individual-specific, microbiome-dependent changes to glycemic responses, warranting follow-up clinical studies to understand long-term impact.
www.cell.com
"Collectively, our study suggests that commonly consumed NNS may not be physiologically inert in humans as previously contemplated, with some of their effects mediated indirectly through impacts exerted on distinct configurations of the human microbiome"
If you accept that gut microbiome is important, then you should consider that fake sugar garbage altering your gut microbiome could have consequences.