You mean consciousness. Having a
full connectome mapped (including the entire optic and nervous system) would HAVE to model a functional human nervous system or, well, it wouldn't be a full map! Why would anyone consider it a full mapping if it doesn't display all the expected neurochemical function of the thing it's supposed to map? The technology has already
progressed far ahead of what leading connectomicists have hoped and concurrent advances in heuristics and computing will only make it faster:
If you're saying that
ion beam microscopy must necessarily scan only DEAD connectomes (because the process is destructive) and there would be no reason to expect that a full connectome scan could approximate a live human... then that would technically be true, but then we'd have a more complete understanding of the human connectome and a functional model could be turned back on more or less like we did with the other connectomes we've virtualized so far, like that poor worm we stuffed into a lego robot.
As to whether our computing substrate have enough Moore's Law expansion in them to accomodate the needs for a human connectome, that's a reasonable qualification. But the IEEE's computing group expects the continued persistence of Moore's Law on IC density for several more DECADES (Moore himself expected the expansion to end by 2025), and the physical limits for computational density on current materials and energy capacity goes as far as the mid 2300's.
As far as consciousness goes there's enough butthurt about quantum states and metaphysical considerations to derail this thread more than it's already been derailed. But it doesn't need to be conscious, it just needs to work.