I dunno about a calculator but the math has been around since, well at least 1969. I'm not sure we can EVER develop a reaction-less drive that isn't a lightsail though, and even with the laser-propelled lightsails you'd still need to bring enough propellant for deceleration until you build a laser at the destination.
The most efficient engines so far are photonic/ion thrusters like the ones Dawn had. It's super slow acceleration (0-60 in four days lol) but with less than 600 pounds of xenon it was able to sustain constant acceleration for 5.9 years. It broke the record in the first six months.
High specific impulse drives like the VASIMR also use noble gases as propellant but it needs big (prolly fissile) generator to produce the 100 kilowatts for the magnetic bottle that will contain and shoot the gas plasma out the back. So you'd have to figure in the mass of the reactor, the drive and propellant. Would still be at least an order of magnitude more efficient than kerolox engines and the specific impulse of the plasma makes it possible to accelerate fast enough to get to Mars in 39 days.
They're saying a Mars mission would need
several VASIMR engines and a ~50MW generator at least. NASA's also got a homegrown magnetoplasma Hall-Effect thruster called the X3 but I dunno how far along it is. VASIMR finished a 100-hour continuous burn trial last year.