Alabama, Alaska, Arizona, California, Florida, Georgia, Indiana, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Montana, Nevada, New Hampshire, North Carolina, North Dakota, Oklahoma, Pennsylvania, South Carolina, Tennessee, Texas, Utah, Virginia, Washington, and West Virginia are all Stand Your Ground states, meaning you have no duty to retreat regardless of where you're attacked.
The top 10 American cities ranked by per capita murders in 2012, in descending order (Flint is #1)
Flint, Michigan - SYG
Detroit, Michigan - SYG
New Orleans, Louisiana - SYG
St. Louis, Missouri - No SYG
Baltimore, Maryland - No SYG
Birmingham, Alabama - SYG
Newark, New Jersey - No SYG
Oakland, California - SYG
Baton Rouge, Louisiana - SYG
Cleveland, Ohio - No SYG
Memphis, Tennessee - SYG
6 SYG vs 4 non SYG doesn't seem like pure chaos. Also, considering that two states made it on the list twice, and given what we know of Flint and Detroit, it seems pretty clear that socio-economic reasons have a lot more to do with the murder rate than self defense laws.