On to the workarounds.
I narrowed down my earlier save game issue to have something to do with stations. I don't know what exactly caused it or how, but I stopped saving while on stations and have not had the issues since. So my first bit of advice is to never save on a station, only while in your ship.
Trading Bugs
Ok, now these are bad but there are workarounds.
Firstly, if your ship bugs out through trading you can clear its trade orders by editing the save game file. It is a a pain in the ass but it works.
Here are the instructions.
Trade ships seem to bug out because of 3 simple but incredibly annoying reasons.
1. The most common cause of the bug is by queuing a sell order for more wares than are
currently on your ship. This means, for example, if you follow the energy trader campaign instructions and queue the 100 energy units sell order before your ship physically has the goods on board it will become bugged. I accidentally avoided this by watching the freighter take delivery before heading out to sell.
So, never execute a sell order before or for more wares than are physically on the ship. This will save you many headaches I promise.
2. If a ship has no cargo drones it won't complete a trade. This is most noticeable on the sell food mission because you are given a construction ship that is technically able to complete trade orders, but it doesn't have any drones on it. So it just flies to the station and sits there. If you like you can buy drones for it at a shipyard.
3. If a ship doesn't have enough cargo drones to make the delivery in one trip. I haven't tested this myself, saw it on a forum post. If you buy cargo drones for a cap ship just make sure you buy enough.
More tips:
* If a ship runs out of Fuel Cells it can travel without them but it will take a VERY long time. It also doesn't seem very capable of finding any on its own. I top off my traders whenever they get down to about half. There is a station in Canterra in f-something that sells them. It is next to the station with the terran leader NPC guy on it.
* Buy a trade computer ASAP. Seriously, this thing is great, if gives you every trade on a station when you buzz it, very handy.
* Use an Xbox controller if you have one. Told 2 of my friends this already and they reported back it was a much better experience.
I'll post more tips if I run across any.